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HAEMATOPOIETIC SYSTEM DISORDERS

Plasma Cell Myeloma

Introduction Plasma cell myeloma (previously referred to as multiple myeloma), is cancer affecting the plasma cells in the bone marrow. These abnormal plasma cells occur in increased numbers and produce abnormal non functional immunoglobulins leading to impaired ability to fight infections in the patient affected, hyperviscosity and renal failure. In the bone marrow the increased …

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Sickle Cell Disease (SCD)

Introduction to Sickle Cell Disease Sickle cell disease is a group of conditions with pathological processes resulting from the presence of Haemoglobin S Usually inherited from the parents who have themselves inherited haemoglobin S. The principal genotypes include: Homozygous sickle cell disease (SS) Sickle cell-haemoglobin C disease (SC) Sickle cell-B thalassaemia (SB thal) Sickle cell-B+ …

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Lymphomas treatment guideline

Introduction to Lymphomas Lymphomas are solid neoplasms that originate in lymph nodes or other lymphatic tissues of the body. They\’re a heterogeneous group of disorders. Can arise at virtually any site More often occurs in regions with large concentrations of lymphoid tissues, e.g. lymph nodes, tonsils, spleen and bone marrow Two main groups of Lymphomas …

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Leukemia

Introduction to Leukemia Leukemia is a heterogeneous group of diseases characterized by infiltration of the blood, bone marrow and other tissues by neoplastic cells of the haematopoietic system Two main types of Leukemia Myeloid leukaemia Lymphoid leukaemia Each of the types is further divided into acute and chronic Acute leukaemias are defined pathologically as blast …

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Anaemia

Introduction to Anaemia Anaemia is a reduction in the haemoglobin concentration in the peripheral blood below the normal range expected for the age and sex of an individual. The World Health Organisation (WHO)defines anaemia by the following haemoglobin (Hb) concentrations: Males < 130 g/L (130-175 g/L) or < 13.5 gram/100 ml.) Females < 120 g/L (120-155 …

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